The Security Room is where Frank West first encounters Brad Garrison, Jessie McCarney, and Otis Washington, as well as where rescued survivors remain and await rescue. It is eventually compromised and zombies can enter it, as is evident in Ending A, B and E, and Overtime.
Frank West arrives at the heliport by Ed DeLuca's helicopter, and passes through the empty Security Room on his way to the Entrance Plaza. Later, after the zombies infiltrate the Entrance Plaza, Frank returns to the Security Room for shelter, where he first encounters Brad Garrison and Jessie McCarney, both DHS agents, as well as Otis Washington, a janitor employed at the mall. Otis welds the door to the Entrance Plaza shut.
Jessie discovers that the signal is blocked by some sort of device, causing her to be unable to call for help. After encountering Russell Barnaby, Frank and Brad agree to temporarily co-operate - Brad will allow Frank to get his scoop if Ed arrives to rescue them in three days.
Jessie spots Carlito Keyes dragging Dr. Barnaby out of the bookstore on the monitors in the Security Room. Brad exclaims that if Carlito carries out whatever he plans on doing with the professor, they may never know what's going on. He heads out to rescue him, with Frank deciding to follow him for the story.
After rescuing Dr. Barnaby, Jessie tends to the injured Brad. She tells Frank that Brad is running a fever from an infected wound, and he needs medicine.
Brad's condition stabilizes after Frank brings back the medicine. Frank tells Jessie that while getting the medicine from the pharmacy, he saved a girl who mentioned Santa Cabeza. Dr. Barnaby overhears them and says that he thought Santa Cabeza was over and done with. Jessie attempts to get him to tell the truth, but he spots Frank and his camera and refuses to speak. Frank says that he will have to get his information from another source.
Later, Frank comes across an injured Isabela in the North Plaza and decides to bring her back. Upon reaching the security room, Frank explains to Brad and Jessie that Isabela is Carlito's sister. Brad pushes for more information on who Carlito is and what his plans are, but Frank says he has no idea. Instead, they decide to question Isabela when she wakes up.
Isabela awakes, and Brad interrogates her. Isabela insists that there was no drug trade in her hometown Santa Cabeza, and explains to Frank and Brad the true story of what occurred in Santa Cabeza. There was an American Research Facility in Santa Cabeza that was directed by Dr. Barnaby. This facility carried out experiments with a wasp that was able to stimulate the appetite of cattle. One day the wasps escaped from the lab and started a zombie outbreak. The US army came for clean up and killed everyone, zombies and humans; apparently the only survivors were Dr. Barnaby, Isabela and her brother Carlito. Several years later, Carlito released the wasp in Willamette to take revenge on the Americans that destroyed his town, and for everyone to know the truth about Santa Cabeza.
While Isabela is relating her story, Dr. Barnaby starts zombifying and attacks Jessie. After struggling a bit, Brad successfully pulls Jessie away. Dr. Barnaby dies after explaining the details of the Santa Cabeza incident. After succumbing to the parasite, Dr. Barnaby reanimates as a zombie and is shot by Brad.
Carlito announces on the intercom system to Isabela, first pleading for her to come back then deciding that he is going to "end it all." After Frank arrives at the Security Room, Isabela explains Carlito's last resort - he is going to blow up the mall and send parasitic larvae into the atmosphere, spreading the virus all over the country. The only chance to stop the explosion is by removing the bombs in the maintenance tunnels while the gas concentration is still low.
After Frank and Brad take care of the bombs, Jessie cheerfully assumes that as soon as Brad captures the terrorist behind the outbreak, it will all be over. Frank confronts Isabela and questions her about her brother's plans, and she suggests they check out his computer in their hideout.
After Frank and Isabela take care of the signal-jamming device, Jessie is able to contact DHS headquarters via an emergency line. She tells them about the Willamette incident. She later calls Frank in a distraught state, telling him that the government has decided to deny everything that has happened. Special Forces soldiers will arrive at midnight to a clean up operation and eradicate all zombies and survivors.
Later, a Special Forces soldier confronts Jessie about the situation, and offers her a chance - if she signs an agreement not to tell anybody about what has happened, she'll be taken into custody and will be free to go.
A second Special Forces soldier guarding the door to the office then hears suspicious noises coming from inside. He investigates and finds a zombified Jessie tearing out the throat of the first soldier. Zombie Jessie can then be found in the Security Room, and all the previously rescued survivors will have disappeared.
A note from Otis found in the Security Room indicates that while Frank was out, the Special Forces arrived via the heliport and started capturing the survivors in the Security Room. He took advantage of the situation and stole a helicopter to escape, though he was unable to find Jessie in the confusion. He adds that he hopes Frank doesn't think he is a coward, and that he owes Frank a drink if they meet on the other side.
Frank returns to the Security Room for a final time to pick up the coffee filters, a key ingredient in the zombification suppressant that Isabela is trying to synthesize.
This is the room that contains the vent leading to the rooftop of Paradise Plaza. It also has an exit to Entrance Plaza, although it is welded shut by Otis Washington. The unlocked clothing and weapons can be found in paper bags in this room. Greg Simpson will remain in this room after being rescued.
This is the main area of the Security Room where cases take place. It contains numerous security cameras that allow Frank, Brad, Jessie, and Otis to observe various locations in the mall. It also contains a green couch for the survivors to rest in when they are tired or injured.
This area leads to the side rooms where the survivors remain. It also contains a staircase that leads up to the heliport. A green couch that can be used to save the game is found in this room. It also contains a PP sticker and the default clothing.
After Frank has rescued the survivors stranded in the mall, they will remain in the side rooms of the Security Room. Depending on which rooms they are in, they may be lost in the mutiny scoops Ronald's Appetite and Kindell's Betrayal.
The following survivors are found in the side room with the purple door:
The following survivors are found in the side room with the yellow door:
- 3 Apples
- 1 in the office on the first day
- 3 after the cutscene showing Brad with additional supplies
- 0 after the third day
- 4 Coffee Creamers
- 2 in the office on the first day
- 4 after the cutscene showing Brad with additional supplies
- 0 after the third day
Different clothing can be worn in the lockers and bags throughout the Security Room, mostly from unlocking achievements, except for Frank's starting clothing and any DLC clothing:
- Prison Outfit
- Special Forces Uniform
- Mega Man Outfit
- Cop Hat
- White Hat
- Pro Wrestling Shoes
- Pro Wrestling Briefs
- Ammo Belt
- Arthur's Boxers