In the Introduction, Irwin was a spectator for the Terror is Reality show at the Fortune City Arena. As soon as Chuck rescued Katey from the green room, Irwin bursts through a pair of locked doors and falls to a ground as a zombie lurches towards him. He manages to get up and flee from the zombie, but falls victim to the awaiting horde that lurked around the corner in the corridor. He is killed and eaten as dozens of zombies swarm around him.
Irwin is featured on the cover of a Fortune City World News magazine issue. He is featured on the bottom lefthand corner with the tagline reading "BALD GUY FINDS CURE FOR BALDING. Even scientists remain hopeful"
Although 121 of the survivors in Dead Rising 2 have 1,000 health, Irwin Sagehorn only has 10.