- "Don't be daydreamin' out here!"
- —Brad, talking to Frank
Brad Garrison is a Department of Homeland Security (DHS) agent that appears in the Willamette Parkview Mall, assigned to the Willamette Incident alongside Jessica McCarney. He fights alongside Frank West throughout the story against Carlito Keyes and is instrumental to learning the truth behind the outbreak. He assumes the responsibility of re-stocking the security room with food and water.
Brad Garrison is a DHS agent encountered in the Entrance Plaza where he shouts out to the survivors to run for the stairs after the zombies broke inside. When Frank is the only one who succeeds in making it to the security room, he orders the mall janitor, Otis Washington, to weld the door shut, preventing any zombie from heading into the security room. Soon after, Brad finds a way back into the mall through the mall air ducts, and heads to go complete his mission: to find and rescue Dr. Russell Barnaby. After Frank follows him in the air ducts, he is asked by Jessie, who followed Frank into the air ducts as well, to aid Brad, who is under fire in the Food Court, and help him find Dr. Barnaby. As Frank enters the Food Court to help, Brad yells at Frank to get into cover. As Frank asks him questions, Brad tells him that they'll talk about it later, after they manage to defeat Carlito. He then gives Frank a handgun, and both men work together to defeat Carlito, but not kill him, as he manages to escape. After he flees, Brad then goes to resume his search for Dr. Russell Barnaby, but is stopped when he finds out Frank knows where he is. At first, Brad stereotypes Frank as a "underhanded, hot-shot paparazzi with nothing better to do than to invade peoples privacy", and is overall uneasy to be around a member of the press. But in the end, he agrees to let Frank follow along as they head for the Entrance Plaza to greet Dr. Barnaby.
They make their way to the Entrance Plaza, where Dr. Barnaby has decided to lock himself in a bookstore, saying he will only leave if it is safe. After learning the news, Brad and Frank go back to the security room empty handed. But while in the security room, Brad learns that Frank is planned to leave the mall in three days time, giving himself newfound hope that he could help Dr. Barnaby out of the mall. He then continues to gather food. After one day in the security room, however, Jessie sees that Dr. Barnaby has been kidnapped by Carlito, and when Brad and Frank find him, Barnaby is suspended one floor above the ground with zombies surrounding below. Carlito is on the second floor, using a sniper rifle to shoot at Brad and Frank. The duo work together once more, and eventually they both manage to defeat him a second time. While fighting Carlito, Brad is able to shoot Carlito in the arm, yet Carlito is able to shoot Brad in the leg, escaping again. Frank then saves Barnaby and brings both of them back to the security room.
Jessie is able to help Brad, suffering from the wound a fever, very little, until Frank is asked to retrieve a medical kit from Seon's Food and Stuff, the local mall supermarket. He succeeds in doing this, ensuring Brad's recovery from his injury.
During the time Brad is healing up, Frank West meets Isabela Keyes, Carlito's sister, and brings her back to the security room after she gets shot from Carlito. When she recovers, Jessie, Frank and Brad interrogate her, to which she tells them about the tragedy of Santa Cabeza. While they are questioning her, Dr. Barnaby comes crashing out of the closet, attacking Jessie. After being thrown off of the woman, he helps all of them understand what really happened at Santa Cabeza, saying that when he was a scientist, he and his team tried to discover how to mass produce cattle, but instead discovered the queen. After the record is set straight, Dr. Barnaby has completed his zombification and Brad shoots Barnaby in the head before he could touch anyone. His mission after that is to simply get as many people out of the mall as possible. As they continue interrogating Isabela, she informs all of them that Carlito is planning on blowing up the mall if all of his plans fail. They all then develop a plan to defuse the bombs; Frank will defuse the bombs, Isabela will inform them all on what's happening, while Brad goes for Carlito.While defusing the bombs Frank comes into contact with Carlito who ends up crashing the van he is driving and starts to shoot at Frank, Brad is able to track Carlito, and pursues him deeper into the zombie-infested maintenance tunnels. He follows him into a storage room, where they engage in a gunfight. While they are fighting in the room, Brad informs him that the bombs are gone thanks to Frank, and that his plans are over. Brad then charges Carlito while he is reloading, catching him off guard, and shoots him in the stomach, mortally wounding him. Brad tells Carlito that his terrorist days are over and just then Carlito pulls a switchblade out and swipes it at Brad thus knocking his gun out of his hands. There is a brief scuffle between the two which eventually results in Carlito stabbing Brad in the shoulder and knocking him outside of the room into a dark, unseeable area, locking the door behind him. As Brad pulls out a flashlight, he sees himself surrounded by copious zombies as reality sinks in that he is doomed. When Frank begins to look for Brad, he discovers him outside of the storage room, disemboweled, and close to zombification. Brad realizes that there is nothing that Frank can do, and tells him to stay away and says he doesn't even feel the pain, and that he is already dead. Before he becomes a zombie, Brad asks Frank not to tell Jessie about this as he slides Frank his gun.
- Photographing Brad as a live zombie will earn the player the Snuff Shot: B achievement.
- After the cutscene Brad will be a zombie, but when the cutscene ends, you will be where you left off when the cutscene began, around 30 feet away from Brad. There is a glitch sometimes where he won't attack Frank if he gets close to him instead Brad will remain motionless.
- Brad Garrison makes a cameo appearance in Frank's Tatsunoko vs. Capcom: Ultimate All-Stars ending along with Jessie.
- In the Dead Rising beta, Brad shares the same last name as David Bailey, whose last name was Garrison. This could mean that Brad's name was different during development.
- His voice actor T.J. Storm also voiced Josh Stone in Resident Evil 5, another game made by Capcom.
- He is a playable character in the mobile version of Dead Rising.
- In the first night, a cutscene plays where he tells Jessie that they will take turns sleeping. He proposes that Jessie will sleep for four hours, and after that he will wake her up and then take his four hour break. Throughout the rest of the night; however, Jessie sleeps on the bed and Brad is never shown taking his turn to rest.
- Zombie Brad can be seen on the cover of Dead Rising. He is the first zombie seen to the right of Frank. He stands out, as he is the only zombie not attacking Frank.